Advanced search
Publication Cover
Autoimmunity Volume 40, 2007 - Issue 8
Submit an article Journal homepage
298
Views
72
CrossRef citations to date
0
Altmetric
Original

PTPN22: Its role in SLE and autoimmunity

Sharon A. Chung Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California, San Francisco, CAUSA
&
Lindsey A. Criswell Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California, San Francisco, CAUSA
Pages 582-590 | Published online: 07 Jul 2009
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

A functional variant of protein tyrosine phosphatase nonreceptor 22 (PTPN22) has recently been shown to be associated with multiple autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, type 1 diabetes, and autoimmune thyroid disease. In this review, we discuss the structure and function of this gene and its disease-associated polymorphisms. In addition, we review the studies investigating the association between this gene and SLE, along with other autoimmune diseases.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later
PDF download + Online access
  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart
* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.