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Inhalation Toxicology
International Forum for Respiratory Research
Volume 21, 2009 - Issue 3
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Research Article

Toxic Neuropathy Due to N-Hexane: Report of Three Cases

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Pages 210-214 | Received 06 Mar 2008, Accepted 29 Jun 2008, Published online: 01 Feb 2009
 

Abstract

Chronic exposure to n-hexane is one of the well known causes of peripheral neuropathy. This type of neuropathy is commonly seen among individuals employed in shoe and bag factories with inadequate ventilation. We describe three patients with acute and sub-acute neuropathy following n-hexane exposure via inhalation of glue. All of the patients had history of working in the same place. The results of laboratory examinations were in normal ranges except the electroneuromyographic (ENMG) findings which were showing the neuropathy. All patients were hospitalized and rehabilitation programs were carried out. Symptomatic relief was achieved following this treatment, however the pathologic ENMG findings still persisted.

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