The publishers would like to apologize for an error that occurred in the paper detailed below. This paper was published in Inhalation Toxicology, 20:245–256, 2008 (ISSN: 0895-8378 print/ 1091-7691 online; DOI: 10.1080/08958370701864250)
Derivation of an Inhalation Reference Concentration Based upon Olfactory Neuronal Loss in Male Rats following Subchronic Acetaldehyde Inhalation
David C. Dorman, Melanie F. Struve, Brian A. Wong, Elizabeth A. Gross, and Carl Parkinson, Gabrielle A. Willson, Yu-Mei Tan and Jerry L. Campbell, Justin G.Teeguarden, Harvey J. Clewell III and Melvin E. Andersen
The published manuscript lacks the pathology incidence tables. These now follow:
Table 1 Incidence (# affected/# examined) of respiratory epithelial inflammation. Bold numbers denote that a statistically significant increase in the incidence of the lesion was seen (vs. air-exposed controls, p< 0.05, Pearson's). Number in parentheses indicate average severity of the lesion seen in animals with a statistically significant lesion incidence. Unaffected animals were excluded from this calculation. 1 = minimal, 2 = slight/mild, 3 = moderate, 4 = moderately severe, and 5 = severe/high). Additional examined nasal regions (see text for details) that were unaffected by acetaldehyde exposure are not included in this Table.
Table 2 Incidence (# affected/# examined) of respiratory epithelial hyperplasia. Bold numbers denote that a statistically significant increase in the incidence of the lesion was seen (vs. air-exposed controls, p< 0.05, Pearson's). Number in parentheses indicate average severity of the lesion seen in animals with a statistically significant lesion incidence. Unaffected animals were excluded from this calculation. 1 = minimal, 2 = slight/mild, 3 = moderate, 4 = moderately severe, and 5 = severe/high). Additional examined nasal regions (see text for details) that were unaffected by acetaldehyde exposure are not included in this Table.
Table 3 Incidence (# affected/# examined) of squamous metaplasia of the respiratory epithelium. Bold numbers denote that a statistically significant increase in the incidence of the lesion was seen (vs. air-exposed controls, p< 0.05, Pearson's). Number in parentheses indicate average severity of the lesion seen in animals with a statistically significant lesion incidence. Unaffected animals were excluded from this calculation. 1 = minimal, 2 = slight/mild, 3 = moderate, 4 = moderately severe, and 5 = severe/high). Additional examined nasal regions (see text for details) that were unaffected by acetaldehyde exposure are not included in this Table.
Table 4 Incidence (# affected/# examined) of olfactory epithelial degeneration or vacuolation. Bold numbers denote that a statistically significant increase in the incidence of the lesion was seen (vs. air-exposed controls, p< 0.05, Pearson's). Number in parentheses indicate average severity of the lesion seen in animals with a statistically significant lesion incidence. Unaffected animals were excluded from this calculation. 1 = minimal, 2 = slight/mild, 3 = moderate, 4 = moderately severe, and 5 = severe/high; P = present). Additional examined nasal regions (see text for details) that were unaffected by acetaldehyde exposure are not included in this Table.