Systematic review on activity of liposomal encapsulated antioxidant, antibiotics, and antiviral agents

Abstract

Reactive oxygen species (ROS) like superoxide anion, hydrogen peroxide, and hydroxyl radical, can be formed as normal products of aerobic metabolism. Overproduction or insufficient removal of ROS results in significant damage to cell structure and functions. Antioxidants applied directly and at relatively high concentrations to cellular systems are effective in protection against the damaging actions of ROS. Microorganisms including Gram-positive and negative bacteria, fungi, protozoa, algae, etc., can be disease causing microorganism. Antimicrobial agents have the capability to inhibitor destroy the microorganisms. The problems arising from the use of antioxidant and antimicrobial agents include poor solubility, instability during storage, low bioavailability, and difficulty to reach target organs with sufficient doses. Liposomal antimicrobial agent and liposomal antioxidants enhance the solubility, bioavailability, and stability of antimicrobial agent and antioxidants.

Keywords:

• Liposome
• antioxidant
• antimicrobial
• free radicles
• microorganisms

Acknowledgments

The authors are grateful for the immense support and cooperation of the management and laboratory members of Centre for Innovations and Technologies (CIT), ADSO Naturals Pvt., Ltd Bangalore.

Disclosure statement

The authors state no conflict of interest and have received no payment in preparation of this manuscript.