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Baylor University Medical Center Proceedings
The peer-reviewed journal of Baylor Scott & White Health
Volume 32, 2019 - Issue 1
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Case Studies

Clomiphene for hypogonadism complicated by polycythemia

Roshirl FranciscoTexas Tech University Health Sciences Center School of Medicine, Lubbock, Texas; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-5710-2011
, BA ORCID Icon,
Sarah JaroudiTexas Tech University Health Sciences Center School of Medicine, Lubbock, Texas; ORCID Iconhttp://orcid.org/0000-0003-2737-4128
, BS ORCID Icon,
Mariam Murtaza AliDepartment of Internal Medicine, Texas Tech University Health Sciences Center School of Medicine at Permian Basin, Texas;
, MD,
Jill FrostDepartment of Pharmacy Practice, Texas Tech University Health Sciences Center School of Pharmacy, Amarillo, Texas;
, PharmD,
Rama ChemitigantiDepartment of Internal Medicine, Texas Tech University Health Sciences Center School of Medicine at Permian Basin, Texas;
, MD &
Alan N. PeirisTexas Tech University Health Sciences Center School of Medicine, Lubbock, Texas; ;Department of Internal Medicine, Texas Tech University Health Sciences Center Clinical Research Institute, Lubbock, Texas; ORCID Iconhttp://orcid.org/0000-0001-9323-7557
, MD, PhD ORCID Icon
Pages 75-77 | Received 24 Jul 2018, Accepted 18 Sep 2018, Published online: 11 Jan 2019
 
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Abstract

Male hypogonadism is associated with poor sexual function. Testosterone therapy via the intramuscular route is the preferred treatment but is associated with secondary polycythemia. We report a patient in whom clomiphene citrate improved hypogonadal symptoms and restored normal free testosterone levels. Clomiphene is inexpensive and can be given orally in secondary hypogonadism. Clomiphene citrate is a promising alternative in patients who develop secondary polycythemia with testosterone.

Acknowledgment

We are appreciative of the assistance received from the Clinical Research Institute at Texas Tech University Health Sciences Center, Lubbock.

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