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Baylor University Medical Center Proceedings
The peer-reviewed journal of Baylor Scott & White Health
Volume 32, 2019 - Issue 1
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Case Studies

Spontaneous bleeding in a patient on enoxaparin with poor renal function

, AB ORCID Icon, , MD, , MD & , MD ORCID Icon
Pages 131-133 | Received 06 Aug 2018, Accepted 24 Sep 2018, Published online: 15 Jan 2019
 

Abstract

Creatinine-based equations are used as standard ways to estimate glomerular filtration rate and kidney function. Unfortunately, serum creatinine varies based on factors such as age, gender, and muscle mass. Overestimation of renal function by creatinine-based equations can be dangerous for renally dosed medications, such as enoxaparin. We present a patient who developed spontaneous bleeding on enoxaparin where kidney function was significantly overestimated by creatinine-based equations. The use of cystatin C levels, which are creatinine independent, can provide a better prediction of renal function.

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