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Baylor University Medical Center Proceedings
The peer-reviewed journal of Baylor Scott & White Health
Volume 32, 2019 - Issue 4
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Editorials

Impact of fossil fuel emissions and particulate matter on pulmonary health

, BSORCID Icon & , PhD
Pages 636-638 | Received 10 Jun 2019, Accepted 05 Jul 2019, Published online: 05 Aug 2019
 

Abstract

In recent decades, several national and international legislative efforts have aimed to improve air quality standards and limit major pollutants, such as carbon monoxide, sulfur dioxide, and nitrogen dioxide, linked to several public health problems. In recent years, particulate matter sources have become an important cause of several pulmonary and systemic diseases. Specifically, several studies examining cigarette smoke particulates have discovered the important contribution that mast cells play in the pathogenesis and progression of smoking-related lung disease and other particulate matter–related lung injury. By understanding the mechanisms of activation and signaling cascades involved in cigarette smoke and mast cell activation, novel pharmacological therapies for particulate matter–induced lung diseases could be developed.

Acknowledgments

The authors thank Dr. Kenneth Nugent at Texas Tech University Health Sciences Center for his advice and support in writing this article.

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