Publication Cover
Baylor University Medical Center Proceedings
The peer-reviewed journal of Baylor Scott & White Health
Volume 35, 2022 - Issue 3
98
Views
1
CrossRef citations to date
0
Altmetric
Case Studies

Immediate reconstruction of segmental mandibular defects via tissue engineering

, DDS, MD, , DDS, MD & , DDS, MD
Pages 391-393 | Received 18 Feb 2021, Accepted 24 Jan 2022, Published online: 03 Mar 2022
 

Abstract

Ameloblastomas are benign, locally invasive odontogenic tumors that comprise approximately 1% of tumors within the jaws, with 66% located in the posterior mandible. If left untreated, these lesions can reach enormous size, resulting in considerable deformity and associated morbidity. Traditionally, defects >6 cm warranted a free-flap fibula transfer or iliac crest autogenous graft. Surgical treatment for the two presented cases included a large (>6 cm) mandibular segmental resection with immediate reconstruction via a tissue-engineering protocol that included bone morphogenetic protein (rhBMP-2), bone marrow aspirate concentrate, and cortical bone chips. Both patients had an uneventful postoperative course and healed satisfactorily. Established bone reconstruction determinants include bone volume, facial counter, esthetics, and restoration of functionality. Advances in tissue engineering provide a legitimate alternative while decreasing the risks, length of hospital stay, and postoperative morbidity.

Log in via your institution

Log in to Taylor & Francis Online

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 37.00 Add to cart

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.