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Journal of Biomaterials Science, Polymer Edition Volume 27, 2016 - Issue 1
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Articles

Tailoring properties of porous Poly (vinylidene fluoride) scaffold through nano-sized 58s bioactive glass

Cijun ShuaiState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha, China
,
Wei HuangState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha, China
,
Pei FengState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha, China
,
Chengde GaoState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha, China
,
Xiong ShuaiState Key Laboratory of Powder Metallurgy, Central South University, Changsha, China
,
Tao XiaoDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, China
,
Youwen DengDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, China
,
Shuping PengSchool of Basic Medical Science, Central South University, Changsha, China;Hunan Provincial Tumor Hospital and the Affiliated Tumor Hospital of Xiangya School of Medicine, Central South University, Changsha, ChinaCorrespondence[email protected]
&
Ping WuCollege of Chemistry, Xiangtan University, Xiangtan, ChinaCorrespondence[email protected]
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Pages 97-109 | Received 15 Sep 2015, Accepted 27 Oct 2015, Published online: 22 Nov 2015
 
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Abstract

The biological properties of porous poly (vinylidene fluoride) (PVDF) scaffolds fabricated by selective laser sintering were tailored through nano-sized 58s bioactive glass. The results showed that 58s bioactive glass distributed evenly in the PVDF matrix. There were some exposed particles on the surface which provided attachment sites for biological response. It was confirmed that the scaffolds had highly bioactivity by the formation of bone-like apatite in simulated body fluid. And the bone-like apatite became dense with the increase in 58s bioactive glass and culture time. Moreover, the scaffolds were suitable for cell adhesion and proliferation compared with the PVDF scaffolds without 58s bioactive glass. The research showed that the PVDF/58s bioactive glass scaffolds had latent application in bone tissue engineering.

Disclosure statement

No potential conflict of interest was reported by the authors.

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