Preparation and properties of gelatin hydrolysate modified with polysiloxane quaternary ammonium salts

Abstract

PSiQAEp-GH polymers were synthesized by the reaction of gelatin hydrolysate (GH) and polysiloxane quaternary ammonium salts containing epoxy group (PSiQAEp) with different molecular weight from 3147 to 12996. The results of FTIR, ¹H NMR and ¹³C NMR showed that the reaction occurred between primary amino group of arginine in GH and epoxy of PSiQAEp. The XRD and DSC studies showed that the degree of short-range order of PSiQAEp-GH reduced and its glass transition temperature (Tg) lowered more than 10 °C compared with GH. The determinations of moisture absorption and contact angle (CA) indicated that the hydrophobility of PSiQAEp-GH was better than GH. The tests of inhibitory zone and minimum bactericidal concentration (MBC) illustrated that the PSiQAEp-GHs exhibited excellent antibacterial activity, and the antibacterial activity depended on both the chemical structure of PSiQAEp-GHs and the biological structure of the bacteria.

Keywords:

• Polysiloxane
• gelatin hydrolysis
• hydrophobic property
• moisture absorption
• antibacterial activity

Acknowledgments

This work was financially supported by the Key Research and Development Program of Shandong Province (No. 2018GGX108002 and No. 2018GGX102023), by the Fund of Shandong Provincial Key Laboratory for Special Silicone-containing Materials (No. 2017-3), and by the Open Project Program for Scientific Research Innovation Team in Colleges and Universities of Shandong Province (No. 2018-3), as well as the Project of Natural Science Foundation of Shandong Province (No. ZR2017LB024).