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Ocular Immunology and Inflammation Volume 14, 2006 - Issue 2
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CASE REPORT

Atopic Optic Neuritis

C. S. Constantinescu Department of Neurology, University Hospital, Queen's Medical Centre, Nottingham, UK
, M.D., Ph.D.,
M. Thomas Department of Immunology, University Hospital, Queen's Medical Centre, Nottingham, UK
&
A. G. Zaman Department of Ophthalmology, University Hospital, Queen's Medical Centre, Nottingham, UK
Pages 125-127 | Accepted 23 Aug 2005, Published online: 08 Jul 2009
 
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Abstract

Purpose: To report a case of optic neuritis associated with atopic dermatitis, which may represent an optic nerve counterpart of atopic myelitis. Methods: Clinical examination, MRI, blood investigations. Results: A 34-year-old man with severe atopic dermatitis developed a steroid-responsive bilateral optic neuritis. Serum IgE was highly elevated, with high titers of mite-specific IgE. Clinical ophthalmological fluctuations paralleled those of atopic dermatitis. Conclusions: The clinical features and parallel fluctuations strongly suggest that the patient's optic neuritis was related to atopic dermatitis. This atopic optic neuritis may represent the optic nerve equivalent of atopic myelitis.

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