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Ocular Immunology and Inflammation Volume 16, 2008 - Issue 3
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CASE REPORTS

Intravascular Lymphoma Masquerading as Vogt-Koyanagi-Harada Syndrome

Patricia J. Pahk Department of Ophthalmology, Lahey Clinic, Burlington, Massachusetts, USA
,
Derrick J. Todd Department of Medicine, Division of Rheumatology, Immunology, Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA
,
Gregory R. Blaha Department of Ophthalmology, Lahey Clinic, Burlington, Massachusetts, USA
,
Sarkis H. Soukiasian Department of Ophthalmology, Lahey Clinic, Burlington, Massachusetts, USA
,
Dan S. Landmann Department of Ophthalmology, Lahey Clinic, Burlington, Massachusetts, USA
,
Donald E. Craven Department of Infectious Disease, Lahey Clinic, Burlington, Massachusetts, USA
,
Bruce S. Tronic Department of Pathology, Lahey Clinic, Burlington, Massachusettes, USA
,
Yuval Zabar Department of Neurology, Lahey Clinic, Burlington, Massachusettes, USA
&
Jeffrey L. Marx Department of Ophthalmology, Lahey Clinic, Burlington, Massachusetts, USA
 show all
Pages 123-126 | Received 12 Oct 2007, Accepted 01 Mar 2008, Published online: 08 Jul 2009
 
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Abstract

Purpose: To describe the clinical course of a case of intravascular lymphoma. Design: Case report. Methods: Retrospective chart review. Results: A 56-year-old man presented with blurry vision associated with fever and decreased hearing. Ocular exam including fluorescein angiography and OCT was consistent with Vogt-Koyanagi-Harada syndrome and the patient initially improved with corticosteroids. Clinical deterioration led to further systemic workup and revealed intravascular lymphoma. The patient was started on chemotherapy with resolution of visual complaints. Conclusions: Intravascular lymphoma can present as a masquerade of VKH syndrome. Diagnosis can be aided with measurement of LDH and skin biopsy.

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