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ABSTRACT
Purpose: To describe the uveitis complications in a large, community-based cohort.
Methods: Retrospective, community-based, cross-sectional cohort study analyzing complications and associations with complications.
Results: A total of 844 cases of uveitis were found; 342 were new-onset, and 462 were prior-onset. In total, 29.5% of patients were affected by one or more complications associated with age, gender, course, and anatomic location of uveitis. Visual loss was experienced by 19.1% of patients and was associated with age, course of disease, and anatomic location of uveitis. Of the patients who developed glaucoma or elevated intraocular pressure over 30 mmHg, 3.9% (n = 33) were related solely to uveitis; 5.2% (n = 44) had an unclear or combined mechanism; and 1.8% (n = 15) were related solely to steroid response. Cystoid macular edema was associated with course of disease and anatomic location of uveitis.
Conclusions: Complications affect a significant portion of uveitis patients, and are often associated with demographic and clinical factors.
ACKNOWLEDGMENTS
Thank you to Aaron Bonham, who provided important statistical assistance in the analysis of these data.
The data herein were presented in part at the American Academy of Ophthalmology Annual Meeting, October, 2009.
DECLARATION OF INTEREST
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.
FUNDING
Funding for the study was provided by a Permanente Medical Group Innovations Grant and the Kaiser Research Foundation Institute Direct Community Benefit Investment Program.