Interventions and Outcomes in Patients with Infectious Pseudomonas scleritis: A 10-Year Perspective

ABSTRACT

Purpose: To identify interventional factors associated with improved visual results and faster time to resolution for patients with Pseudomonas scleritis.

Methods: Retrospective study analyzing inciting factors, therapeutic modalities, and outcomes of patients with Pseudomonas scleritis.

Results: A total of 24 patients were analyzed; 22 were treated as outpatients. All had resolution of infection and 58% (n = 14) maintained ≥20/200 vision. Medical therapy included topical and oral antibiotics; seven received additional subconjunctival injections; two were admitted for IV antibiotics. Patients presenting with ≥20/200 vision were more likely to maintain this level of vision (n = 8, 80%) compared to those presenting with severe vision loss (n = 5, 36%) (p = 0.04). A similar proportion of patients who received (n = 8, 61%) and did not receive (n = 5, 39%) oral steroids achieved 20/200 vision or better once infection resolved, p = 1.0.

Conclusions: Pseudomonas scleritis can be successfully managed in the outpatient setting. Oral steroids do not appear harmful in the treatment of this disease.

Keywords:

• Infectious scleritis
• Pseudomonas
• review
• steroids

DECLARATION OF INTEREST

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

Funding

This manuscript was supported by grants from NIH Center Core Grant P30EY014801 and Research to Prevent Blindness Unrestricted Grant.

Additional information

Funding

This manuscript was supported by grants from NIH Center Core Grant P30EY014801 and Research to Prevent Blindness Unrestricted Grant.