Analysis of the Clinical Profile and Management of Inflammatory Choriodal Neovascular Membranes in Uveitic Eyes: A Study from a Tertiary Referral Center

ABSTRACT

Purpose: To analyze clinical profile and management of inflammatory choroidal neovascularization (CNV) seen at a referral uveitis clinic.Methods: Records of patients with uveitis and inflammatory CNV from January 1989 to April 2012 were retrieved and the data was analyzed.Results: Forty-nine eyes of 43 patients were included. Mean age at presentation was 35.81 years. Eighteen eyes (36.7%) had infective etiology and 31 eyes (63.2%) had non-infective etiology. The most common location of the CNV was subfoveal, in 18 eyes (36.7%). Management included corticosteroids in all patients, additional immunosuppressive in 17 eyes (34.6%) and local management, with anti-VEGF injections in 29 eyes (63%). Visual outcome was favorable in 37 eyes (75%).Conclusion: Inflammatory CNV can be successfully managed and vision can be improved or stabilized, with prompt and adequate therapy of the underlying uveitic disease coupled with additional local therapy to selectively target the CNV.

Keywords:

• Anti-VEGF
• CNV
• corticosteroids
• immunosuppressive
• tuberculosis

DECLARATION OF INTEREST

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.