ABSTRACT
Purpose: To describe the demographics and clinical characteristics of pediatric uveitis and scleritis at a tertiary eye care center.
Methods: Clinical records of children with either uveitis or scleritis that presented between January 1989 and January 2016 were reviewed retrospectively.
Results: Seventy-three patients were identified. Fifty-four had uveitis and 19 had scleritis. Posterior uveitis was the most common (27.8%), followed by intermediate uveitis (25.9%), panuveitis (25.9%) and anterior uveitis. Majority were noninfectious uveitis (37.0%), and 29.6% were idiopathic. Common associations were sarcoidosis (14.8%), HLA-B27 haplotype (9.3%) and toxoplasmosis (7.4%). Posterior scleritis was more common (94.7%) than anterior scleritis and majority were idiopathic (68.4%). Delayed patient presentation and presenting visual acuity worse than 0.3 LogMAR were associated with poor visual outcome (p = .03; OR = 0.17; 95% CI, 0.03–0.84 and p = .007; OR = 0.09; 95% CI, 0.02–0.52 respectively).
Conclusion: Majority had noninfectious etiologies. Uveitis associated with juvenile idiopathic arthritis was rare.
Clinical trial registration
SingHealth Centralized Institutional Review Board, Singapore; R1428/11/2017, ClinicalTrials.gov; NCT03472781. https://clinicaltrials.gov/ct2/show/NCT03472781
Declaration of interest
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.