The Treatment Models for Adenoviral Keratoconjunctivitis in the Childhood Population

ABSTRACT

Purpose: To examine the effects of treatments performed on children with adenoviral conjunctivitis.

Methods: 50 children with Adenoviral keratoconjunctivitis (AK) were evaluated. Patients were divided into four groups according to the medical treatment agents that were used previously. AK symptoms were clinically scored and analyzed. The diagnosis of all children was confirmed by an in-office lateral flow immunoassay.

Results: Fifty patients with AK were included in the study. 24 (48%) were female and 26 (52%) were male. The mean age was 12.88 ± 2.66 (8–17). In PVP-I groups clinical findings shows faster improvement than other groups (p < .05).

Conclusions: Conjunctival irrigation with 2.5% PVP-I is very effective for the treatment of adenoviral conjunctivitis in childhood. Ganciclovir ophthalmic gel 0.15% increases the effect of 2.5% PVP-I on AK, but this was not statistically significant.

KEYWORDS:

• Adenoviral keratoconjunctivitis
• childhood population
• medical treatment agents
• povidone-iodine
• antiviral treatment

Authors Contribution

SB, EE: considered and designed the study; SB, EE: collected the results; SB: analysis and clarification of data; EE: composing the reports; EE: design of the output, improving the research critically for essential intellectual contents; All contributors confirmed the latest modification of the manuscript.

Competing interests

The authors (SB and EE) declared that there are no financial and conflicting interests to disclose.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

This report was approved by the University of Health Sciences Dr. Behcet Uz Child Disease and Pediatric Surgery Training and Research Hospital, Izmir, Turkey research ethics committee and followed the tenets of the Declaration of Helsinki.

Additional information

Funding

No specific bequests have been taken from any financial companies in the public, commercial or non-profit sectors.