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Ocular Immunology and Inflammation Volume 30, 2022 - Issue 2
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Research Article

Effect of Fundus Fluorescein Angiography on Semiautomated Aqueous Flare Measurements

Muhammad Sohail Halima Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California, USA;b Ocular Imaging Research and Reading Center, Sunnyvale, California, USAORCID Iconhttps://orcid.org/0000-0003-3208-7078
, MDORCID Icon,
Neil Onghansenga Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California, USA
, MD,
Jung Hyun Parka Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California, USA
, MD, PhD,
Mervenur yilmazc Department of Ophthalmology, Gazi University, School of Medicine, Ankara, Turkey
, MD,
Asadu Segawac Department of Ophthalmology, Gazi University, School of Medicine, Ankara, Turkey
, MD,
Mestan Ertopc Department of Ophthalmology, Gazi University, School of Medicine, Ankara, Turkey
, MD,
Muhammad Hassana Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California, USA
, MD,
Anh Nt Trana Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California, USAORCID Iconhttps://orcid.org/0000-0002-8819-3876
, BSORCID Icon,
Zeynep Aktasc Department of Ophthalmology, Gazi University, School of Medicine, Ankara, Turkey
, MD,
Sengul Ozdekc Department of Ophthalmology, Gazi University, School of Medicine, Ankara, Turkey
, MD,
Gokhan Gurelikc Department of Ophthalmology, Gazi University, School of Medicine, Ankara, Turkey
, MD,
Diana V. Doa Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California, USA
, MD,
Yasir J. Sepaha Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California, USA
, MBBS,
Quan Dong Nguyena Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California, USA
, MD, MSc &
Murat Hasanreisoglua Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California, USA;c Department of Ophthalmology, Gazi University, School of Medicine, Ankara, Turkey;d Department of Ophthalmology, Koc University Medical School, Istanbul, Turkey;e Research Center for Translational Medicine, Koç University, Istanbul, TurkeyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-9885-5653
, MDORCID Icon show all
Pages 424-427 | Received 04 Jun 2020, Accepted 17 Jul 2020, Published online: 23 Sep 2020
 
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ABSTRACT

Purpose

To evaluate the effects of fluorescein fundus angiography (FFA) on semiautomated aqueous flare measurements

Methods

Laser flare photometer (LFP) measurements was performed at baseline, 30 min, and 4 h after the intravenous administration of sodium fluorescein dye. FFA was performed immediately after the baseline LFP measurement. LFP values at 30 min and 4 h after FFA were compared to baseline values. Mean change in LFP measurements at 30 min and 4 hafter baseline was compared between FFA arm and controls.

Results

The mean flare measurement in the FFA and control arm dropped 6% (p value = 0.002) and 9% (p value = 0.04), respectively. Mean change in LFP measurement at 30 min and 4 h after baseline was not significant between FFA arm and controls.

Conclusions

Administration of fluorescein dye does not increase LFP values. The decrease in the LFP measurement following FFA may be attributed to dilation drops.

Declaration of Interest

None of the authors has conflict of interest with the submission. No financial support was received for this submission.

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