ABSTRACT
Purpose
To describe the characteristics seen on multispectral imaging (MSI) in patients with punctate inner choroidopathy (PIC) and choroidal neovascularisation (CNV) and compare the findings with current standard multimodal imaging techniques.
Methods
This is a retrospective observational case series of 10 patients with PIC complicated by CNV that underwent multimodal retinal imaging examinations.
Results
Twelve eyes of 10 patients were included. CNV was identified in 11 of the 12 eyes (91.7%) by MSI with nodular or trunk-like hyperreflectance on retinal oxy/deoxyhemoglobin map. MSI revealed choroidal vasculature around CNV in 91.7% eyes and pathological changes including retinal pigment epithelial atrophy and melanin disruption of punctate lesions in all eyes.
Conclusion
MSI helps in noninvasively detecting CNV in PIC patients and observing associated changes in choroidal vasculature. This imaging technique is also a promising tool for better tracking pathological changes of PIC lesions complementary to current standard multimodal imaging modalities.
Acknowledgments
The authors would like to thank Cheng Sun, Sha Li, Ziyang Li, and Bo Liu for supporting this study and Mr. Ribaric Zeljko for supporting spectral technology review. Jie Zhang and Minfang Zhang contributed to the work equally and should be regarded as cofirst authors.
Declaration of interest
The authors report no conflicts of interest.