ABSTRACT
Purpose
To describe the clinical and microbiological features, management strategies, outcomes, and challenges in post-cataract surgery nocardia endophthalmitis.
Methods
We evaluated 28 eyes with culture-confirmed Nocardia endophthalmitis following cataract surgery. Data were collected regarding age, gender, clinical presentation, management modalities used, and final outcomes.
Results
Mean age of the patients was 66.07 + -8.6 years. Four eyes (14.3%) underwent early pars plana core vitrectomy, while 18 eyes (64.3%) underwent tap/inject regimen followed by observation for 48 h, with or without a delayed vitrectomy. Thirteen eyes (46.4%) received amikacin treatment. Visual acuity (VA) improved from presentation in 9/28 (32.1%) eyes, worsened in 14/28 (50%) eyes, and showed no change in 5/28 eyes (17.9%).
Conclusions
We did not find any significant association between functional outcome and time of surgery or presenting VA. Additional amikacin may be considered if there is a strong suspicion of nocardia endophthalmitis, as it may help in achieving better anatomical outcomes.
Acknowledgments
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
Declaration of interest
Authors have no conflict of interest to declare