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Invited Review

Epidemiology of Viral Induced Anterior Uveitis

, MD, PhDORCID Icon, , DNB, , FRCOphth, FRCS(Ed)ORCID Icon & , MD, PhD
Pages 297-309 | Received 17 Aug 2020, Accepted 15 Nov 2020, Published online: 22 Feb 2021
 

ABSTRACT

Purpose

Viral agents are the most common cause of infectious anterior uveitis worldwide. The purpose of this review is to analyze the frequency, gender and racial differences of viral anterior uveitis (VAU) in various populations.

Methods

Systematized literature review of epidemiological reports of VAU cited in PubMed, EMBASE and the Cochrane Library database published until June 30th, 2020.

Results

A total of 12 clinical studies on epidemiology of definite VAU and 36 clinical studies of presumed VAU were identified. Members of Herpesviridae family represent the most common causes of VAU. Other less frequently reported causes, such as rubella and endemic viruses (HTLV-1, Chikungunya, Dengue, Ebola, Zika virus) were also analyzed.

Conclusion

HSV, VZV are prevalent worldwide. CMV is more frequent in Asia, and rubella in the West. However, due to globalization and air travel, HTLV-1, Chikungunya, Dengue and Ebola may become important causes of VAU across the world.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper

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