ABSTRACT
Aim
To identify risk-factors for developing endophthalmitis following open globe injury (OGI) in children.
Methods
Retrospective, single-center, case-control study of children aged <18 years who sustained OGI.
Results
Our cohort of 93 eyes consisted of 30 cases (Group A- endophthalmitis) and 63 controls (Group B- no endophthalmitis). Twenty-four eyes (80%) diagnosed with endophthalmitis presented after 24 hours of injury. The presence of central corneal zone-1 injuries (Odd ratio [OR]: 6.64, p= 0.001) and vitreous in wound (OR: 3.53) were associated with the risk of developing endophthalmitis. (p= < 0.05) Additionally the presence of iris prolapse (OR: 4.76) and posterior capsular rupture (PCR) (OR: 5.80) increased the risk of developing endophthalmitis.(p <0.05) . Streptococci was isolated in 15 eyes, Pseudomonas in 3 eyes, and Candida in 1 eye. The visual outcomes at three months were significantly worse in Group A (LogMAR 1.77±1.06) compared to Group B (LogMAR 0.65±0.68)(p<0.05).
Conclusion
Central corneal involvement, vitreous/ iris incarceration and PCR were important risk factors for development of PTE in children
Declaration of interest
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.