XEN45 Gelstent Implantation in the Treatment of Glaucoma Secondary to Fuchs Uveitis Syndrome

ABSTRACT

Purpose

Evaluation of treatment efficacy of XEN45 gelstent for glaucoma secondary to Fuchs uveitis syndrome (FUS).

Methods

This retrospective case series evaluated patients with glaucoma secondary to FUS, who underwent XEN45 implantation. Complete success was defined as IOP lowering of ≥ 20% and cutoff IOP at $\le$18 mmHg. Success was qualified if additional glaucoma medication was necessary. Additional glaucoma surgery except for needling and open bleb revision was regarded as failure.

Results

Twelve eyes of 12 patients were included. Qualified and complete success rates were 50% after one year (n = 10). Qualified success was achieved in 66.6% of patients with 33.3% of patients achieving complete success after two years (n = 6).

Conclusions

XEN45 implantation had some success in the treatment of glaucoma secondary to FUS, but needling was frequently necessary to improve outcome.

KEYWORDS:

• uveitic glaucoma
• minimally invasive glaucoma surgery
• phacoemulsification
• heterochromia iridis
• FUS

Acknowledgments

We thank Prof. Dr. Philipp Berens, Werner Reichardt Centre for Integrative Neuroscience, Institute for Ophthalmic Research, University of Tuebingen, Tuebingen, Germany and Dr. Gunnar Blumenstock, Institute for Clinical Epidemiology and Applied Biometry, University of Tuebingen, Tuebingen, Germany, for statistical advice.

Declaration of interest statement

Hanna has no conflicts of interest to declare. Vanessa Guggenberger received a travel grant from Santen. Bogomil Voykov has received honoraria for talks from Allergan.

Correction Statement

This article has been corrected with minor changes. These changes do not impact the academic content of the article.

Additional information

Funding

Hanna Faber receives research funding from the Junior Clinician Scientist program of the Faculty of Medicine, Eberhard Karls University of Tuebingen, Germany (application number 463–0–0) and from the German Research Foundation (Deutsche Forschungsgemeinschaft) [DFG, EXC 2064 ML Number 390727645].