Acute Thyroiditis and Bilateral Optic Neuritis following SARS-CoV-2 Vaccination with CoronaVac: A Case Report

ABSTRACT

Purpose

To describe a case of acute thyroiditis and bilateral optic neuritis associated with SARS-CoV-2 vaccination.

Methods

A single case report from a tertiary referral center.

Results

The patient described in the following case report developed acute thyroiditis and bilateral optic neuritis following SARS-CoV-2 vaccination. The patient underwent pulse therapy followed by oral tapering corticosteroid therapy with an improvement of the bilateral disc swelling and the visual field, and recovery of thyroid-stimulating hormone to the normal limits.

Conclusion

Although the association between immunization and the onset of demyelinating manifestations of the central nervous system is well documented, this is the first reported case of bilateral optic neuritis and acute thyroiditis and subsequent to administration of vaccination against SARS-CoV-2.

KEYWORDS:

• COVID-19
• vaccination
• optic neuritis
• CoronaVac
• adverse effect

Acknowledgments

All authors had full access to all of the data in the study and take responsibility for the integrity of the data. The authors have no conflicts of interest to declare.

Disclosure statement

All authors certify that they have no affiliations with or involvement in any organization with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.