Hypopyon after Periocular Corticosteroid Injection: A Case Series

ABSTRACT

Purpose

The purpose of this study was to describe a case series of hypopyon after periorbital corticosteroid injection.

Methods

This was a retrospective, observational case series investigating hypopyon cases after injection of periorbital steroid patients.

Results

We presented three patients manifested hypopyon after periocular corticosteroid injection. All three cases were diagnosed as HSV stromal keratitis or endotheliitis and treated successfully with topical steroids as well as systemic and topical antiviral treatment.

Conclusion

HSV keratitis is not recommend when treated with periocular corticosteroid injection. Topical corticosteroid is the best choice for HSV stromal keratitis and HSV endotheliitis.

KEYWORDS:

• Anti-virus
• corticosteroid
• herpes simplex virus
• herpes simplex virus keratitis
• hypopyon
• periocular injection

Acknowledgments

The authors would like to express our sincere thanks to the Dr. Jing Hong and Dr. Huijuan Wu for the treatment consulting.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This project was supported by Peking University Medicine Seed Fund for Interdisciplinary Research [BMU2018MX003].