ABSTRACT
Purpose
To present four cases of posterior ophthalmic manifestations associated with a temporal relationship to SARS-CoV-2 vaccination.
Methods
Retrospective case series with a review of clinical findings.
Results
Four patients presented with various posterior ophthalmic findings including uveitis, maculopathy, and optic neuropathy. Each of their clinical courses varied in terms of ophthalmic imaging and exam findings.
Conclusion
The coronavirus disease 2019 (COVID-19) pandemic has ushered in a new wave of challenges to healthcare, epidemiological endeavors, and widespread vaccination efforts. Novel vaccines have been developed for the SARS-CoV-2 virus, including both mRNA and viral vector-based platforms. The ocular manifestations and side effects related to the SARS-CoV-2 vaccine is not well established or understood. There may be an association between vaccination and posterior ophthalmic manifestations.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Ethical statement
IRB approval was obtained by WCG (Number 2618575-44547747). The requirement for consent was waived by the Ethics Committee.
Summary statement
Case series of four patients with posterior ophthalmic manifestations following a SARS-CoV-2 (COVID-19) vaccine discussing clinical presentation, treatment, and outcomes.