Ocular Involvement of Brucellosis: A Pooled Analysis Study

ABSTRACT

Aim

Brucellosis may affect the eye to varying degrees. The aim of this study was to investigate the ocular involvement of brucellosis and highlight key points.

Material and Methods

Published literature in English language on the ocular involvement of brucellosis within last 30 years was evaluated. The PubMed international database was screened using certain keywords.

Results

The study included 27 publications evaluating a total of 159 cases. The most common types of ocular involvement were uveitis (52.2%) and conjunctivitis (17.6%). Most cases had concomitant systemic brucellosis (27.7%), and the most commonly used diagnostic method was a serological test (92.4%). Of all the patients, 37.1% recovered with sequelae.

Conclusion

Brucellosis may cause a wide range of ophthalmic manifestations, and an overlooked or late diagnosis may also lead to the development of sequelae or loss of vision. A routine ophthalmologic examination should be performed in all patients with systemic brucellosis.

KEYWORDS:

• Brucella
• brucellosis
• endophthalmitis
• ocular involvement
• pooled analysis
• uveitis

Acknowledgments

We thank Prof. Feyza Onder for sharing the fundus photo.

Disclosure statement

The authors declare that they do not have any conflict of interest.

Ethics submission

Since the study was designed as literature research, ethics committee approval was not required.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.