Comment on Maghsoudlou et al. Titled “Uveitis Associated with Monogenic Autoinflammatory Syndromes in Children”

ABSTRACT

The work by Maghsoudlou et al. provides a comprehensive examination of monogenic autoinflammatory syndromes (MAIS) in children, with a specific focus on uveitis as a significant clinical manifestation. It meticulously details the genetic underpinnings, clinical features, diagnostic criteria, and current therapeutic strategies, including the use of biologics. This critique highlights the strengths of the review and suggests further exploration in areas such as long-term treatment outcomes, genotype-phenotype correlations, and the impact of MAIS on quality of life. Future research could benefit from longitudinal studies and enhanced predictive models to improve management and treatment personalization.

KEYWORDS:

• Biologic therapies
• genetic syndromes
• genotype-phenotype correlation
• quality of life
• uveitis

Disclosure statement

No potential conflict of interest was reported by the author(s).

CRediT authorship contribution statement

Gokul Sudhakaran: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.