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Review

Strabismus and amblyopia in Africa – a systematic review and meta-analysis

, OD, PhDORCID Icon, , OD, PhDORCID Icon, , OD, MSc, MPH, , ODORCID Icon, , OD, PhDORCID Icon, , OD, MScORCID Icon, , ODORCID Icon, , OD, MScORCID Icon & , OD, MScORCID Icon show all
Pages 31-44 | Published online: 28 Dec 2022
 

ABSTRACT

The objective of this review was to estimate the prevalence of strabismus and amblyopia in Africa. A systematic online literature search was conducted for articles on strabismus and amblyopia in Africa. Meta-analysis was performed, using the Freeman-Tukey double arcsine transformation, to estimate the prevalence of strabismus and amblyopia in Africa. Subgroup analyses were conducted according to age, gender, study year, and type of amblyopia. Meta-regression was used to evaluate the influence of predetermined factors on the prevalence of amblyopia. 8 (1 population-based & 7 school-based) and 21 (3 population-based & 18 school-based) studies on strabismus and amblyopia with sample sizes of 22,355 and 46,841, respectively, were included in the review. Overall prevalence of strabismus in Africa was estimated to be 0.8% (95% CI: 0.4% − 1.4%); exotropia was 0.2% (95% CI: 0.1% − 0.5%) and esotropia was 0.5% (95% CI: 0.1% − 1.2%). Overall prevalence of amblyopia was estimated to be 0.6% (95% CI: 0.3% − 0.9%); refractive and strabismic amblyopia were 1.1% (95% CI: 0.2% − 2.5%) and 0.4% (95% CI: 0.2% − 0.6%), respectively. Prevalence estimate of amblyopia in males was 1.8% (95% CI: 0.7% − 3.3%) and in females was 1.3% (95% CI: 0.4% − 2.6%). There was a significant association between the prevalence of amblyopia and the type of amblyopia (p = .007) and the study year (p = .006). Although there appears to be a relatively low prevalence of strabismus and amblyopia in Africa, there is a dearth of well-designed population-based studies on strabismus and amblyopia in Africa, resulting in the lack of epidemiological information on strabismus and amblyopia within the general African population. Information about the prevalence of strabismus and amblyopia across Africa can inform policy making and design and implementation of public health intervention program.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.

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