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Research Article

Fungal Keratitis in the Egyptian Delta: Epidemiology, Risk Factors, and Microbiological Diagnosis

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Pages 198-205 | Received 20 Oct 2020, Accepted 05 Apr 2021, Published online: 15 Apr 2021
 

ABSTRACT

Purpose

The current study evaluates the epidemiological characteristics, risk factors, and microbiological diagnosis of fungal keratitis among patients living in the Egyptian Delta.

Methods

This is a prospective hospital-based study that included patients who were clinically diagnosed and confirmed by culture test to have fungal keratitis. Patients were examined at baseline and risk factors were identified and collected. Patients were followed over 6 months and the outcomes were documented.

Results

A total of 171 (67%) of 252 microbial keratitis patients was proved fungal by microbial culture test. Rural residence and agricultural activity were reported in 139 (81.3%) and 85 (49.7%) patients, respectively. Patients presented within 1 week from the start of symptoms were 120 (70.2%). A total of 54 (31.6%) patients reported ocular trauma. Forty patients (23.4%) had prior ocular surgery and 43 (25.1%) patients had a history of previous ocular disorders. Aspergillus species was the most common organism found in 120 (70.17%) patients, followed by Dematiceous fungi that were found in 25 (14.6%) patients. The main outcome was corneal opacity in 132 (77.2%) patients following medical treatment.

Conclusion

Filamentary fungal predominance in Mansoura is influenced by the rural residence of its population. Therefore, more efforts in spreading awareness about microbial keratitis among villagers are important to reduce blindness caused by corneal opacity in rural areas.

Acknowledgments

Our sincere thanks to the director of Mansoura Ophthalmic Hospital in Mansoura for being supportive throughout all the stages of this research. Our sincere thanks to Ahmed Ashraf for the hard work done during the statistical analysis done for this study.

Declaration of interest

None of the authors has any proprietary interests or conflicts of interest related to this submission

Disclaimer

This submission has not been published anywhere previously and it is not simultaneously being considered for any other publication. This submission has not been submitted or reviewed by any journal.

Financial support

No financial support was obtained for this work

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