Affectations in photic and thermic circadian entrainment of the locomotor activity rhythm in obese volcano mouse Neotomodon alstoni

ABSTRACT

Obesity affects the ability of both photic and non-photic entrainment of the locomotor activity's circadian rhythm in the volcano mouse Neotomodon alstoni. The present study aimed to recognize differences in the synchronization of semi-natural, artificial, and periods other than 24 h light cycles between lean and obese mice. Also, the entrainment to temperature cycles was explored. The results obtained indicate that the activity profiles show discrete differences in the amplitude according to the type of lighting; when exposed to 22 or 26 h photic cycles, obese mice manifest more difficulty in the entrainment of the circadian rhythm. Changes in the free-running period produced by temperature cycles were larger in lean mice than in obese mice, with variability among organisms. The above confirms that photic entrainment is more difficult in obese mice, and that temperature entrainment suggest a decreased sensibility to temperature cycles in obese mice.

KEY WORDS:

• Circadian Rhythms
• Photic and Thermic Entrainment
• Obesity
• Neotomodon alstoni

Acknowledgments

Melisa Y. Mendoza-Ávila for her support on acquisition data software.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by Dirección General de Asuntos del Personal Académico (DGAPA, PAPIIT IN212118) to Manuel Miranda Anaya.