Sleep disturbances in women with polycystic ovary syndrome

Abstract

Sleep disturbances in women with Polycystic Ovary Syndrome (PCOS) have been reported in recent years. The majority of published studies are related to Obstructive Sleep Apnea (OSA) while not many researches have analyzed any other causes of sleep disturbances. A group of ninety five women with Polycystic Ovary Syndrome were enrolled into the study. Sleep disturbances were assessed using validated questionnaires. On the grounds of Athens Insomnia Scale (AIS) evaluation a clinically significant insomnia was ascertained in 12.6% of women with PCOS, while according to Insomnia Severity Index (ISI) in 10.5%. Clinically significant insomnia according to both AIS and ISI, occurred significantly more often in women with PCOS than in women without PCOS based on the chi-square test. The Mann–Whitney U test revealed statistically significant difference between women with and without PCOS based on total values of ISI. An excessive daytime sleepiness occurred at 7.4% of women with PCOS. Statistically significant dependance between: clinically significant insomnia in both AIS and ISI and excessive daytime sleepiness indicated by Epworth Sleepiness Scale (ESS) was observed. Sleep disorders are common in women with PCOS. Screening assessment of sleep disturbances should be a part of medical diagnostics in women with PCOS.

Chinese abstract

近年来有多囊卵巢综合征 (PCOS) 患者睡眠障碍的报道。大多数发表的研究都与阻塞性睡眠呼吸暂停 (OSA) 有关, 然而并非很多研究分析了其他导致睡眠障碍的原因。该研究纳入了95名多囊卵巢综合征患者。睡眠障碍通过有效的问卷调查进行评估。通过雅典失眠量表 (AIS) 评估临床显著的失眠, 多囊卵巢综合征患者发生率为12.6%, 然而通过失眠严重程度指数 (ISI) 评估, 其发生率为10.5%。经卡方检验, 通过AIS 及 ISI评估的临床显著失眠的患者, 多囊卵巢综合征组发生率显著高于非多囊卵巢综合征组。Mann-Whitney U检验显示: 基于ISI评估的总分值, 多囊卵巢综合征组和非多囊卵巢综合征组的差异具有统计学意义。多囊卵巢综合征患者白天过度嗜睡发生率为7.4%。通过AIS 及 ISI评估的临床显著失眠与Epworth嗜睡量表 (ESS) 评估的白天过度嗜睡之间具有显著的统计学关系。多囊卵巢综合征患者睡眠障碍是常见的。睡眠障碍的筛查评估应作为多囊卵巢综合征患者医疗诊断的一部分。

Keywords:

• Anxiety
• depression
• PCOS
• sleep disorders

Declaration of interest

The authors report no conflicts of interest.