Follicular growth but absence of oocyte and cumulus maturation during ovarian stimulation in the days following surgical abortion: a case report

Abstract

This paper is a case report on the results of an ovarian stimulation performed in the days following an induced abortion. A patient had breast cancer diagnosed during an early pregnancy. She had an induced abortion and had, before chemotherapy an ovarian stimulation, using rFSH and GnRH antagonist, followed by follicular puncture for oocyte for vitrification in the view of fertility preservation. No oocyte could be obtained despite a good hormonal and ultrasonographical follicular growth. This case report suggest that ovarian stimulation must be delayed after abortion to allow the maturation of oocyte-cumulus complexes

Chinese abstract

本文是一篇个案报告, 报道关于人工流产后几天进行卵巢刺激的结果。一名患者在妊娠早期被诊断为乳腺癌。她进行了人工流产, 在化疗前进行了卵巢刺激, 用rFSH和GnRH拮抗剂, 随后进行穿刺取卵, 玻璃化冻存卵细胞以保存生育能力。尽管有很好的荷尔蒙和超声显像的卵泡生长, 但没能获得卵母细胞。这一个案报告表明：人工流产后必须延迟卵巢刺激, 才能使卵母细胞-卵丘复合体成熟。

Keywords:

• Abortion
• breast cancer
• oocyte maturation
• ovarian stimulation
• pregnancy

Declaration of interest

The authors report no conflict of interest and no funding for this study.