Women with inflammatory bowel diseases have a suboptimal cervical cancer screening rate and are not aware of the recommended human papilloma virus vaccine

Abstract

The aim of the study was to assess the self-reported cervical cancer screening rate among patients with inflammatory bowel diseases (IBD) and patient attitude towards human papilloma virus (HPV) vaccination. A self-designed survey was conducted in hospitalized IBD patients. The survey comprised demographic data, questions regarding cervical smear test frequency and vaccinations recommended for an IBD patient. Randomly, patients completed the survey with a physician present to determine question comprehension. In order to provide test–retest reliability a group of 10 patients completed it twice. Survey data from 150 IBD patients (mean age: 36 years, SD ± 13; mean IBD duration: 10 years, SD ± 6.5) were analyzed. Fifteen percent of the patients reported irregular cervical testing and 15% do not remember when having had a previous cervical testing performed. Only 69% of the patients undergo testing regularly; 30% annually, 32% every 2–3 years; 7% every 5 years. The mean age of patients tested regularly was 22 years, vs. 32 years tested irregularly (p < .001). Only 10% of women claimed that HPV vaccine is recommended for an IBD patient. There is a low adherence to the recommendations regarding cervical cancer screening and prophylaxis. Better multi-disciplinary cooperation between patients and physicians is required to improve patient education and outcomes.

Chinese abstract

炎性肠病患者宫颈癌筛查率不理想且不知晓注射人乳头瘤病毒疫苗的推荐

摘要

本研究的目的是评估炎性肠病（IBD）患者的自报宫颈癌筛查率和对人乳头瘤病毒（HPV）疫苗接种的态度。在住院患者中进行了自行设计的调查。调查内容包括人口统计学相关数据, 宫颈涂片筛查频率问题及向IBD患者推荐疫苗接种。患者随机的在与医师一同在场完成调查, 以保证对问题的理解。为了调查的重测信度, 每组10名患者完成了2次调查。对来自150名IBD患者的数据进行了分析（平均年龄：36岁, SD ±13;平均IBD持续时间：10年, SD ±6.5）。15%的患者有不定期的宫颈癌筛查, 15%不明确是否曾进行过筛查。只有69%的患者定期进行筛查；30%患者每年筛查一次, 32%每2-3年筛查1次；7%患者每5年筛查1次。定期进行筛查女性的平均年龄为22岁, 不定期筛查患者的平均年龄为32岁（p <.001）。只有10%的女性知晓对于IBD患者推荐应用HPV疫苗。IBD患者对宫颈癌筛查和预防建议的依从性低, 需要改善患者和医生之间的多学科合作, 以改善对患者的教育及预后。

关键词: 炎性肠病；人乳头瘤病毒；宫颈癌筛查；预防；患者依从性

Keywords:

• Inflammatory bowel disease
• human papilloma virus
• cervical cancer screening
• prevention
• patient adherence

Acknowledgements

The authors declare that they did not receive funding for this work.

Disclosure statement

There are no conflicts of interest to report.