Mother’s age at menopause but not own age at menarche has an impact on ovarian reserve

Abstract

To detect clinical parameters impacting ovarian reserve, data were analyzed from 573 patients who had an anti-Müllerian hormone (AMH) measurement for infertility treatment. No impact was found on the age at menarche but a significant diminished ovarian reserve was observed when a patient’s mother was menopausal before age 50. These data suggest that ovarian reserve must be monitored in such patients to offer them fertility preservation when at risk of premature ovarian insufficiency (POI).

Chinese abstract

卵巢储备功能受母亲绝经年龄影响而与自身初潮年龄无关

摘要

为了检测影响卵巢储备功能的临床指标, 我们对573例不孕症患者治疗前检测的抗苗勒氏管激素（AMH）的数据进行分析。研究发现, 母亲绝经年龄小于50岁的患者卵巢储备功能显著下降, 而与其自身初潮年龄无关。以上数据表明, 在为具有早发性卵巢储备功能不全（POI）风险的患者提供生殖力保护时必须监测其卵巢储备功能。

关键词: 抗苗勒氏管激素, 月经初潮, 绝经, 早发性卵巢功能不全

Keywords:

• AMH
• menarche
• menopause
• premature ovarian insufficiency

Disclosure statement

The authors report no conflict of interest.

Funding

There was no funding for this study.