Chronic pelvic pain improvement: impact on quality of life and mood

Abstract

Women with chronic pelvic pain (CPP) frequently suffer from mood disturbances and reduced quality of life. Whether pain improvement ameliorates mood and quality of life is still unclear, and it was investigated in an observational prospective study performed in a cohort of 117 of the outpatient services for endometriosis and chronic pelvic pain at a University Hospital. Depending on disease, women were treated either by surgery or by the administration of an estrogen–progestin or a progestin alone. Pain during menses, between menses and at intercourse was evaluated by a 100 mm visual analog (VAS) scale. Quality of life was evaluated by the SF-36 questionnaire, state of anxiety by the Y-1 form of the State-Trait Anxiety Inventory (STAI-Y1) and depression the Self Evaluating Depression Scale (SDS). Women were 34.2 ± 8.1 years old. After a mean follow-up period of 10.0 ± 9.1 months, and independently on treatment (43.6% surgery), pain during menses (−28.2 ± 36.8; p<.0001), between menses (−11.3 ± 37.1; p<.002) and at intercourse (−8.3 ± 35.4; p<.02) decreased. SF-36 increased (3.3 ± 16.2; p<.03), STAI slightly decreased (−1.9 ± 8.6; p<.02), while depression did not change (−0.7 ± 7.8; p=.36). Pain changes were not related to changes of SF-36 or mood scores. In women with CPP, prolonged pain amelioration, has little impact on mood, particularly on depression. The data support the need for a multidisciplinary approach to women with CPP.

摘要

患有慢性盆腔疼痛(CPP)的妇女经常有情绪障碍和生活质量下降。疼痛改善是否可以改善情绪和生活质量目前尚不清楚。我们在一家大学附属医院对门诊的117名患有宫内膜异位症和慢性盆腔疼痛的患者进行了一项观察性前瞻性研究。根据病情不同, 对这些女性进行了手术治疗、雌孕激素或单纯孕激素治疗。用100mm视觉模拟评分量表(VAS)对月经期疼痛、经间期疼痛和性交时疼痛进行评估。通过SF-36问卷对生活质量进行评估, 通过状态-特质焦虑量表Y-1 (STAI-Y1)和抑郁自评量表(SDS)评价焦虑和抑郁状态。女性年龄为34.2 ± 8.1岁。经过治疗（43.6%为手术治疗）后平均随访时间10.0 ± 9.1月, 经期疼痛 (-28.2 ± 36.8；p<.0001), 经间期疼痛 (-11.3 ± 37.1；p<.002) and性交疼痛(-8.3 ± 35.4；p<.02)评分均有降低。 SF-36评分升高(3.3 ± 16.2; p<.03), STAI评分轻微降低(-1.9 ± 8.6; p<.02), 然而抑郁评分无改变(-0.7 ± 7.8; p=.36)。疼痛的改变与SF-36评分和情绪评分变化无关。对有慢性盆腔疼痛（CPP）的女性, 长期疼痛的改善, 对患者情绪的影响很小, 特别是对抑郁的影响。这些数据支持患有CPP的妇女需要采取多学科的治疗方式。

The Chinese abstracts are translated by Prof. Dr. Xiangyan Ruan and her team: Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.

Keywords:

• Chronic pelvic pain
• endometriosis
• quality of life
• anxiety
• depression
• mood

Disclosure statement

No potential conflict of interest was reported by the authors.