Evaluation of ovarian function using three dimensional ultrasound in perimenopausal women

Abstract

To evaluate the feasibility and clinical value of three-dimensional ultrasound in evaluating ovarian function in perimenopausal women. In this prospective cohort study, 102 patients with clinically suspected perimenopause and 90 patients with menopause were enrolled. These patients were classified into three groups according to the level of follicle stimulating hormone (FSH) and estradiol (E2): menopause group, perimenopause group, and normal group. Perimenopause group: There were significant differences in volume, vascularization index (VI), flow index (FI), and vascularization-flow index (VFI) in the ovaries after treatment. Cycle 1 > cycle 0 (p  < .05) and cycle 3 <cycle 0 (p < .05) in FSH. Menopause group: There were significant differences in volume, VI, FI, and VFI of the ovaries after treatment: Cycle 3 >cycle 0 (p < .05), and in FSH: cycle 3 < cycle 0 (p < .05). Three-dimensional ultrasound in ovarian quantitative measurement can objectively reflect the change in the ovarian function, predicting the effect of drug treatment, and provided an objective information for early intervention to menopausal.

摘要

目的：探讨三维超声在围绝经期妇女卵巢功能评估中的可行性及临床价值。在这项前瞻性队列研究中, 102例临床可疑的围绝经期患者和90例绝经期患者被纳入研究。根据卵泡刺激素(FSH)和雌二醇(E2)水平分为绝经组、围绝经期组和正常组。围绝经期组：治疗后卵巢体积、血管化指数(VI)、血流指数(FI)、血管化血流指数(VFI)有显著性差异。FSH中第1周期>第0周期(p<.05)和第3周期< 0周期(p<.05)。绝经组:治疗后卵巢体积、VI、FI、VFI有显著性差异:周期3 >周期0 (p< 0.05), FSH：周期3<周期0 (p< 0.05)。三维超声卵巢定量测量能客观反映卵巢功能变化, 预测药物治疗效果, 为绝经期早期干预提供客观信息。

The Chinese abstracts are translated by Prof. Dr. Xiangyan Ruan and her team: Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.

Keywords:

• Three dimensional ultrasound
• quantitative measurement
• ovarian function
• perimenopausal

Disclosure statement

The authors of this work have nothing to disclose.

Additional information

Funding

This study was supported by Zhejiang Province Public Welfare Technology Application Research Project (Project No:2014C33158).