Assessment of premature menopause on the sexual function and quality of life in women

Abstract

Introduction

Premature Ovarian Insufficiency (POI) is characterized by ending menstruation in women under 40 years of age. It has a significant effect on women's sexuality and mental health and quality of life. This study aimed to evaluate the sexual function and quality of life of premature menopausal women.

Methods

This study was a case-control study on 132 people (66 women with a diagnosis of POF and 66 women of reproductive age with normal ovarian function) who were matched in terms of the age, presenting to Women's Clinic in Jahrom in 2019. The WHOQOL-BREF questionnaire and the Female Sexual Function Index (FSFI) questionnaire were used to collect data. p < .05 was considered statistically significant.

Results

The mean score of sexual function in premature menopausal women was 21.35 ± 4.82 and in non-menopausal women was 25.4 ± 6.61 (OR = 0.11, 95% CI = 0.04–0.28). All areas of sexual function; desires disorder (OR = 0.21 95% CI = 0.07–0.56), Arousal disorder(OR = 0.28, 95% CI = 0.08–0.93), orgasm disorder (OR = 0.36 95% CI = 0.16–0.80), lubrication disorder (OR = 0.21 95% CI= 0.05–0.78), satisfaction disorder (OR = 0.11, 95% CI = 0.04–0.28) and quality of life domains: physical health (OR = 0.4 95%CI = 0.06–0.3), mental health (OR = 0.28 95% CI = 0.06–0.1), environmental health (OR = 0.22 95%CI = 0.04–0.6) and social health (OR = 0.28 95%CI = 0.01–0.2) saw a decrease in the premature menopausal women group compared to the control group.

Conclusion

The results demonstrated that premature menopausal women are found to be weaker than the control group in all areas of sexual function and quality of life. Among the areas of sexual function, such as libido, arousal, satisfaction, and pain have the most impact on quality of life. Therefore, based on the results from improving sexual function, this issue can improve the quality of life.

摘要

目的：早发性卵巢功能不全(POI)是指女性在40岁之前绝经。它对女性的性行为、心理健康和生活质量有重大影响。本研究旨在评估早绝经对女性性功能和生活质量的影响。

方法：本研究是一项病例对照研究, 研究对象为2019年在贾赫罗姆妇科诊所就诊的132名女性, 其中包括确诊为POF和卵巢功能正常的育龄女性各66名。采用WHOQOL-BREF问卷和女性性功能指数(FSFI)问卷收集数据。P< 0.05被认为具有统计学意义。

结果：POI女性的性功能评分为21.35±4.82, 正常女性为25.4±6.61(OR=0.11, 95% CI=0.04–0.28)。在性功能方面：性欲障碍(OR=0.21 95% CI=0.07–0.56)、性唤起障碍(OR=0.28, 95% CI=0.08–0.93)、高潮障碍(OR=0.36 95% CI=0.16–0.80)、润滑障碍(OR=0.21 95% CI=0.05–0.78)、满足障碍(OR=0.11 95% CI=0.04–0.28)和生活质量方面:躯体健康(OR=0.4 95% CI=0.06–0.3)、精神健康(OR=0.28 95% CI=0.06–0.1)、环境卫生(OR =0.22 95% CI=0.04–0.6)和社会健康(OR=0.28 95% CI=0.01–0.2), 与对照组相比, POI组均较低。

结论：结果表明POI女性在性功能和生活质量的所有方面都比对照组差。在性功能方面, 性欲、性唤起、性满足和疼痛对生活质量影响最大。因此, 改善性功能可以提高生活质量。

Keywords:

• Sexuality
• premature
• menopause
• women

Acknowledgement

We would like to appreciate the officials and staff of the Jahrom Clinic and all those who helped us in this study.

Ethical considerations

The authors state that in this study, all relevant ethical principles have been observed, including the confidentiality of the questionnaires, the informed consent of the participants in the research, and the authority to withdraw from the research. This research was conducted after obtaining permission from the ethics committee of Jahrom University of Medical Sciences with the number IR.JUMS.REC.1398.078).

Disclosure statement

The authors have no conflicts of interest to declare