108
Views
24
CrossRef citations to date
0
Altmetric
Pregnancy

Macrosomia in well controlled CSII treated Type I diabetic pregnancy

, , , , &
Pages 611-613 | Received 23 May 2007, Accepted 19 Jun 2008, Published online: 07 Jul 2009
 

Abstract

Objective. To survey the effect of tight glycemic control by insulin pumps, of pre-gestational Type 1 diabetic women on pregnancy outcome.

Methods. Twelve consecutive Type 1, insulin pump treated, diabetic patients followed in the high risk maternal – fetal clinic were ascertained. Data regarding glucose control was assessed and correlated with pregnancy outcome.

Results. A total of 14 deliveries (10 singleton) were assessed. There were no miscarriages, one baby that was born with a ventricular septal defect (VSD). Glycemic control was within the acceptable guidelines. HbA1c (%) by trimesters: 6.5 ± 0.9, 5.9 ± 0.7, 5.8 ± 0.6 and average glucose (mg/dL) 121.0 ± 15.2, 114.8 ± 13.2, 116.0 ± 21.1. Average birth weight was 3312.1 ± 750.2 g with five babies (35%) weighting over 4.0 kg at birth. Birth weight was significantly correlated with HbA1c at the first trimester, mean glucose at trimester 1 and 2, and maternal weight at delivery (r = 0.74, p = 0.045; r = 0.72, p = 0.051; r = 0.74, p = 0.046; r = 0.74, p = 0.04, respectively).

Conclusions. Our study of a limited number of patients suggest that women with pre-gestational diabetes obtaining acceptable glycemic goals with insulin pump therapy have increased risk of macrosomia. Current glycemic goals and therapies in treating pre-gestational diabetic patients therefore might not be sufficient to normalise pregnancy outcomes in of women with pre-gestational diabetes.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access
  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart
* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.