Publication Cover
AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 23, 2011 - Issue 4
119
Views
4
CrossRef citations to date
0
Altmetric
SHORT REPORTS

Correlates of poor perceived health among individuals living with HIV and HBV chronic infections: a longitudinal assessment

, , , , , , , , , & show all
Pages 501-507 | Received 27 Oct 2009, Published online: 25 Jan 2011
 

Abstract

Chronic hepatitis B virus (HBV) infection affects up to 14% of people living with HIV and AIDS (PLWHA) and is associated with a higher risk of non-AIDS death. While great advances have been made in the therapeutic management of co-infection with HIV and HBV, nothing is known about perceived health in people living with HIV and HBV. This study aimed at characterizing individuals with poor perceived overall health among 308 HIV–HBV co-infected individuals enrolled between May 2002 and May 2003 in a three-year French cohort. A binary score for perceived overall health (good vs. poor) was calculated from individuals’ responses to the COOP-WONCA charts at cohort enrolment and at quarterly visits throughout the follow-up. Mixed models were used to explore factors associated with this score. At enrolment, 190 individuals (62%) reported poor overall health. In the multivariate analysis, low CD4 percentage, co-infection with hepatitis C or D viruses, HIV diagnosis before 1996 and HBeAg positivity were independently associated with poor perceived overall health. Poor perceived health concerns a considerable portion of individuals living with HIV and HBV. Individuals with wild-type HBV and multiple hepatitis infection require better clinical management. Further research is needed for hepatitis D virus infection, for which treatment options are currently very limited.

Acknowledgements

The authors would like to thank Jude Sweeney for the English revision and editing of the manuscript. This work was funded by SIDACTION, the French national agency for research on HIV/AIDS and viral hepatitis (ANRS, Agence Nationale de Recherches sur le Sida et les hépatites virales), with a special grant from Gilead Sciences, and sponsored by IMEA (Institut de Médecine et d'Epidémiologie Appliquée).

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 53.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 464.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.