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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 30, 2018 - Issue 9
159
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Articles

Trends in discharges from the HIV/AIDS ward at a tertiary Canadian Hospital from 2005 to 2014

, , ORCID Icon, , , , , , , & show all
Pages 1099-1106 | Received 09 Sep 2017, Accepted 23 Jan 2018, Published online: 04 Feb 2018
 

ABSTRACT

Advances in HIV therapies have transformed HIV infection into a manageable chronic disease. Accordingly, hospital admission trends among people living with HIV may have evolved over time. This study describes discharge diagnoses from the dedicated HIV/AIDS ward at St. Paul’s Hospital in Vancouver, Canada. A retrospective database review of admissions to the HIV/AIDS ward between 1 July 2005 and 30 June 2014 was conducted. Primary discharge diagnoses were manually categorized by condition and reviewed by two physicians. Data were analysed in 12-month intervals. Trends were fitted using generalized estimating equations. A total of 1595 individuals with 3919 admissions were included. The median age was 46 years, 77.1% identified as male, 63.6% had a history of injection drug use (IDU) and 61.8% had a history of hepatitis C virus exposure. The most common reasons for admission included non-opportunistic respiratory tract infections (18.2%), cellulitis (7.3%), gastroenteritis (6.0%), endocarditis/bacteremia (4.9%) and bone/joint infections (3.5%). The proportion of admissions attributable to opportunistic infections declined from 16.2% in 2005 to 5.5% in 2014. Over this period, the proportion of individuals on antiretroviral therapy and with virologic suppression increased (odds ratio 1.19 [95% confidence interval 1.16, 1.23] and 1.22 [95% confidence interval 1.17, 1.26], respectively). These results demonstrate a decline in admissions related to opportunistic infections but increased admissions due to other infections among people living with HIV. Preventive and outpatient care for respiratory infections and complications of IDU may further improve health care outcomes and decrease hospital admissions in this setting.

Acknowledgements

We thank the participants in the BC HIV/AIDS Drug Treatment Program as well as the physicians, nurses, social workers and volunteers who support them. The 10C HIV/AIDS Ward database was supported and maintained by the BC Centre for Excellence in HIV/AIDS. DJ is supported by the Clinician Investigator Program, University of British Columbia.

Disclosure statement

No potential conflict of interest was reported by the authors.

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