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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 32, 2020 - Issue 8
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Articles

Anticipated stigma and medication adherence among people living with HIV: the mechanistic roles of medication support and ART self-efficacy

Chengbo Zenga South Carolina SmartState Center for Healthcare Quality, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA;b Department of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3512-1115View further author information
ORCID Icon,
Xiaoming Lia South Carolina SmartState Center for Healthcare Quality, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA;b Department of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, USAView further author information
,
Shan Qiaoa South Carolina SmartState Center for Healthcare Quality, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA;b Department of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, USAView further author information
,
Xueying Yanga South Carolina SmartState Center for Healthcare Quality, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA;b Department of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, USAORCID Iconhttps://orcid.org/0000-0001-6788-0688View further author information
ORCID Icon,
Zhiyong Shenc Guangxi Center for Disease Control and Prevention, Nanning, People’s Republic of ChinaView further author information
&
Yuejiao Zhouc Guangxi Center for Disease Control and Prevention, Nanning, People’s Republic of ChinaView further author information
Pages 1014-1022 | Received 08 Jul 2019, Accepted 29 Jan 2020, Published online: 26 Apr 2020
 
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ABSTRACT

This study aimed to examine the relationship between anticipated stigma and medication adherence as well as the mechanistic roles of medication support and ART self-efficacy. Data were derived from the baseline assessment of a prospective cohort study in Guangxi, China. A total of 1198 PLWH were recruited and assessed on their sociodemographic characteristics, medication adherence, anticipated stigma, medication support, and ART self-efficacy. Path analysis was used to examine the direct effect from anticipated stigma to medication adherence and indirect effects through medication support and ART self-efficacy. Path model revealed that the indirect effect from anticipated stigma to medication adherence was statistically significant while the direct effect was not significant. Anticipated stigma could influence medication adherence through ART self-efficacy but not through medication support. The serial mediating effect of medication support and ART self-efficacy on the relationship between anticipated stigma and medication adherence was significant. Anticipated stigma affects medication adherence among PLWH through its adverse impact on medication support and ART self-efficacy. Tailored interventions promoting medication support and ART self-efficacy may alleviate the negative influence of anticipated stigma on medication adherence among PLWH. Additionally, policy efforts aiming to reduce stigma against PLWH and increasing medication support are warranted to improve medication adherence among PLWH.

Acknowledgements

The authors wish to thank all participants who gave of their time for the current study, and the reviewers for their helpful comments.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This study was supported by the National Institute of Health (NIH) Research Grant R01MH0112376 by National Institute of Mental Health.

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