Annular pustular psoriasis in a 14-month-old girl: a therapeutic challenge

Abstract

Annular pustular psoriasis (annular PP) is a rare but severe variant of psoriasis, which may even occur in early childhood. At this age, therapeutic options are limited and medication issues can be challenging. We report clinical features, diagnostic findings and treatment of an 11-month-old girl with annular PP. Oral acitretin therapy was initiated at 0.9 mg/kg/d and gradually tapered after complete resolution in the subsequent 10 months without relapse. Acitretin proved to be a highly effective therapeutic option in an infant with annular PP.

Keywords:

• Acitretin
• annular pustular psoriasis
• children
• psoriasis
• psoriasis of erythema annulare centrifugum-type

Disclosure statement

Henning Hamm is coordinating investigator of a German multicenter study on fumaric acid esters in children and adolescents with plaque psoriasis sponsored by Biogen GmbH, Ismaning, Germany, and participated in an advisory board meeting on pediatric psoriasis by invitation of AbbVie Deutschland GmbH & Co. KG, Wiesbaden, Germany. The other authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.