Patients opinion and adherence to antimalarials in lupus erythematosus and rheumatoid arthritis treatment

Abstract

Objective: To obtain the opinion of patients with rheumatoid arthritis or lupus erythematosus about the use of antimalarials through questionnaires and to evaluate their adherence to medication.

Methods: A cross-sectional study of patients treated with antimalarial medication for a period equal to or longer than 1 year attended between November 2012 and October 2014. A structured questionnaire with 12 questions was filled out.

Results: Among 300 patients examined, 92% (275) used medication regularly. Hydroxychloroquine was used by 55% (166) of patients, chloroquine by 25% (75), and 20% (59) reported using both medications at different moments. Most of the patients (221 or 74%) were using medication seven days a week and had taken it for a period longer than 5 years; 61% (182) considered the treatment good and said, 21% (63) said, ‘It is good, but I’m afraid of taking it’. Most of the patients (70% or 211) did not report any adverse symptoms. Their main claim was related to blurred vision, which was solved by a refraction examination.

Conclusions: Fear has been a factor that makes adherence to treatment difficult. Making patients aware of the importance of the treatment is strongly relevant because antimalarials are well tolerated.

Keywords:

• Antimalarial maculopathy
• lupus erythematosus
• rheumatoid arthritis
• questionnaires
• adherence to treatment

Acknowledgments

The project was approved by the Ethics Committee in Research located on the ground floor of Pedro Ernesto University Hospital, CAAE: 06114912.2.0000.5259, Date October 17 2012.

Disclosure statement

No potential conflict of interest was reported by the authors.