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International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine Volume 45, 1984 - Issue 2
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Original Article

Possible Association of Membrane and Nuclear Changes in γ-irradiated Rat Thymocytes

E.A. Zherbin Department of Clinical Radiobiology, Central Research Institute of Roentgenology and Radiology, The U.S.S.R. Ministry of Public Health, Leningrad, 188646, U.S.S.R.
&
A.B. Chukhlovin Department of Clinical Radiobiology, Central Research Institute of Roentgenology and Radiology, The U.S.S.R. Ministry of Public Health, Leningrad, 188646, U.S.S.R.
Pages 179-183 | Received 07 Apr 1983, Accepted 22 Sep 1983, Published online: 03 Jul 2009
 
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Summary

γ-irradiated rat thymocytes were incubated in medium containing fresh rat serum. After 6 hours in culture, an equal dose dependency was noted for nuclear pyknosis and the loss of surface receptors to autologous erythrocytes. Decreased rosette formation preceded the expression of pyknosis. A possible relation between the membrane changes and pyknosis during interphase death of the thymocytes is discussed.

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