Abstract
Physico‐chemical factors affecting the toxicity of Ni2+, Hg2+ and Cu2+ to Cylindrospermum IU 942 were investigated. Hg2+ was more toxic to the test organism than Ni2+ and Cu2+ (Hg2+> Ni2+> Cu2+). The toxicity of metals to Cylindrospermum was mitigated by pH, chelators and amino acids. Investigated heavy metals were more toxic to the growth of Cylindrospermum at acidic pH than at alkaline pH. EDTA was a more effective chelator than citrate. Glutamine was found to play a protective role against metal toxicity.