Biological activity of aqueous extracts of Southern Brazilian mushrooms

ABSTRACT

This study aims to perform a bioactive analysis of five mushrooms collected in south of Brazil. The total phenol content of the extracts was equivalent to the antioxidant activity by ACAP assay. All extracts were able to inhibit the growth of Acinetobacter baumanni, and Auricularia auricula and Lactarius deliciosus extract showed the best antibacterial activity. In addition, no extract showed cytotoxic activity against VERO cells at the highest concentration evaluated (2500 µg/mL). Our results showed better antioxidant activity through the inhibition of the oxidation via peroxyl radical. It can be observed that all extracts were active against A. baumanni, and even moderately, all extracts could be inhibited of at least one of the bacteria used in the study. Added for these, the aqueous extracts showed no toxicity in VERO cells, highlighting the importance of research about the active compounds of mushrooms of the region.

KEYWORDS:

• Antioxidant potential
• antibacterial activity
• biome pampa
• basydiomicetes

Acknowledgments

The authors are grateful to Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES). The quimical analyses are supported by Núcleo de Experimentação e Estudos Analíticos belonging to IF/RS – Campus Sertão, under responsibility of Msc. Denise Billibio. The Laboratório de Biologia, Ecologia e Aplicação de Fungos da UFPel – Campus Capão do Leão, had a key role in the identification of mushrooms species. Author received a Master Science fellowship by CAPES, Brazil.

Conflict of Interest

Authors declare that they have no conflict of interest.

Additional information

Funding

No financial support was received for this study.