Light physical activity predicts long-term mortality in individuals with a different cardiovascular health status: a cohort study

ABSTRACT

Studies have showed that LIPA seems to be favorably associated with mortality in the general population and illness individuals, but the association between different cardiovascular health status and mortality is not clear.  After adjustment , the HRs of LIPA in individuals with CVRF and CVD from quartiles 2–4 were less than 1, which were 0.78 (95%CI, 0.61 ~ 0.99; P = 0.042), 0.63 (95%CI, 0.47 ~ 0.83; P = 0.001), 0.55（95%CI, 0.40 ~ 0.76; P < 0.001）, and 0.52 (95%CI, 0.37 ~ 0.74; P < 0.001)，0.39 (95%CI, 0.27 ~ 0.58; P < 0.001), 0.33 (95%CI, 0.22 ~ 0.51; P < 0.001)  LIPA is beneficial for reducing mortality, but the shape of the association depends on cardiovascular health status.

KEYWORDS:

• Physical activity
• cardiovascular diseases
• health status
• mortality
• cohort studies

Abbreviations

BMI, body mass index; BP, blood pressure; CI, confidence interval; CVD, cardiovascular disease; CVRF, cardiovascular risk factors; HDL, high-density lipoprotein; HR, hazard ratio; ICD-10, International Statistical Classification of Disease and Related Health Problems 10th Revision; LDL, low-density lipoprotein; LIPA: light physical activity; MACE, major adverse cardiovascular events; MET, metabolic equivalent of task; MV, moderate to vigorous; MVPA, moderate to vigorous physical activity; PA, physical activity; STROBE, Strengthening the Reporting of Observational Studies in Epidemiology

Acknowledgment

The authors thank the National Health and Nutrition Examination Survey participants, staff, and investigators.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Ethics approval and consent to participate

The National Center for Health Statistics Research Ethics Review Board approved the NHANES 03–04 (Protocol #98–12) and NHANES 05–06 cycles (Protocol #2005–06). All participants provided written informed consent.

Additional information

Funding

Chenglong Wang was supported by the National Natural Science Foundation of China (81874410). The funders had no role in the study design or implementation, data collection, and analysis, or manuscript preparation.