Genomic-wide analysis approach revealed genomic similarity for environmental Mexican S. Oranienburg genomes

ABSTRACT

As the human population grows, an increase in food trade is needed. This elevates the risk of epidemiological outbreaks. One of the prevalent pathogens associated with food production in Mexico has been Salmonella Oranienburg. Effective surveillance systems require microbial genetic knowledge. The objective of this work is to describe the genetic composition of Mexican S. Oranienburg genomes. For that, 53 strains from different environmental sources were isolated and sequenced. Additionally, 109 S. Oranienburg genomes were downloaded. Bioinformatic analyses were used to explore the clonal complex and genomic relatedness. A major clonal group formed by ST23 was identified comprising four STs. 202 SNPs were found the maximum difference among isolates. Virulence genes for host invasion and colonization as rpoS, fimbria type 1, and, T3SS were found common for all isolates. This study suggests that Mexican S. Oranienburg strains are potential pathogens circulating continuously in the region between host and non-host environments.

KEYWORDS:

• S. Oranienburg
• genome comparison
• SNP
• Sequence Type (ST)
• epidemiology

Acknowledgements

This genomic material was provided by The National Laboratory for Food Safety and Research (LANIIA) at Centro de Investigación y Desarrollo A.C (CIAD) at Culiacán, Sinaloa, México. Also to Célida Isabel Martínez Rodríguez for all the technical support and facilities provided during this research.

Authors contribution

Formal analysis and investigation: José Roberto Aguirre-Sánchez and Inés Fernando Vega-López. Writing – original draft: José Roberto Aguirre-Sánchez, José Andrés Medrano-Félix and Jaime Martínez-Urtaza. Writing – review and editing: Nohelia Castro del Campo. Resources: Jaime Martínez-Urtaza and Cristóbal Chaidez-Quiroz. Supervision: Cristobal Chaidez-Quiroz.

Disclosure statement

No potential conflict of interest was reported by the authors.

Supplemental data

Supplemental data for this article can be accessed online at https://doi.org/10.1080/09603123.2023.2191312.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.