Advanced search
Publication Cover
International Journal of Food Sciences and Nutrition Volume 72, 2021 - Issue 8
Submit an article Journal homepage
639
Views
5
CrossRef citations to date
0
Altmetric
In vitro and animal studies

Paraprobiotics obtained by six different inactivation processes: impacts on the biochemical parameters and intestinal microbiota of Wistar male rats

Caroline N. Almadaa Department of Food Science and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas, SP, BrazilView further author information
,
Carine N. Almada-Érixa Department of Food Science and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas, SP, BrazilView further author information
,
Aline R. Roquettob Department of Food and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas, SP, BrazilView further author information
,
Valfredo A. Santos-Juniorc Department of Physical Education, Federal University of Great Dourados, Dourados, MS, BrazilView further author information
,
Lucélia Cabrald Institute of Biosciences, Department of General and Applied Biology, São Paulo State University, Rio Claro, SP, BrazilView further author information
,
Melline F. Noronhae Research Informatics Core, Research Resource Center, University of Illinois at Chicago, Chicago, IL, USAView further author information
,
Any Elisa S. S. Gonçalvesf Internal Medicine Department, Faculty of Medical Sciences, University of Campinas, Campinas, SP, BrazilView further author information
,
Philipe dos Santosg Department of Food Engineering and Technology, Faculty of Food Engineering, University of Campinas, Campinas, SP, BrazilView further author information
,
Andrey dos Santosf Internal Medicine Department, Faculty of Medical Sciences, University of Campinas, Campinas, SP, BrazilView further author information
,
Julian Martinezg Department of Food Engineering and Technology, Faculty of Food Engineering, University of Campinas, Campinas, SP, BrazilView further author information
,
Pablo C. Lolloc Department of Physical Education, Federal University of Great Dourados, Dourados, MS, BrazilView further author information
,
Whyara K. A. Costah Department of Food Engineering, Federal University of Paraíba, João Pessoa, PB, BrazilView further author information
,
Marciane Magnanih Department of Food Engineering, Federal University of Paraíba, João Pessoa, PB, BrazilORCID Iconhttps://orcid.org/0000-0002-7771-0479View further author information
ORCID Icon &
Anderson S. Sant’Anaa Department of Food Science and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas, SP, BrazilCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-5052-2315View further author information
ORCID Icon show all
Pages 1057-1070 | Received 13 Dec 2020, Accepted 17 Mar 2021, Published online: 05 Apr 2021
 
Sample our Food Science & Technology journals, sign in here to start your access, latest two full volumes FREE to you for 14 days

Abstract

This study investigated the effects of feeding paraprobiotics obtained by six processes [heat, ultrasound, high pH, low pH, irradiation and supercritical carbon dioxide (CO2)] on biochemical parameters and intestinal microbiota of Wistar male rats. Daily administration of paraprobiotics did not affect (p ≥ 0.05) the food intake, body weight, glucose and triglycerides levels, expression of antioxidant enzymes or thermal shock proteins in comparison to the control. Bifidobacterium lactis inactivated by irradiation and supercritical CO2 decreased the total cholesterol levels in serum (p < 0.05). Bifidobacterium lactis inactivated by supercritical CO2 increased the albumin and creatinine levels, while decreased the HDL-cholesterol levels (p < 0.05). Clostridiales (45.6–56%), Bacteroidales (31.9–44.2%) and Lactobacillales (3.9–7.8%) corresponded to the major orders in paraprobiotic groups. The properties of paraprobiotics are dependent on the method of inactivation, the intensity of the method employed and on the strain used.

Acknowledgements

The authors would like to thank Pablo Vasquez for the irradiation of probiotic bacteria in the Institute for Energy and Nuclear Research (IPEN), São Paulo, Brazil.

Disclosure statement

No potential conflict of interest was reported by the author(s),

Data availability statement

The data that support the findings of this study are available in Sequence Read Archive of the National Centre for Biotechnology Information (NCBI), reference number under the Bio-Project ID PRJNA628744.

Additional information

Funding

This work was supported by the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) [302763/2014-7 and 305804/2017-0] and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES-Brazil; Finance code 001).

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 910.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.